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2.
J Clin Endocrinol Metab ; 106(2): e602-e614, 2021 01 23.
Статья в английский | MEDLINE | ID: covidwho-914177

Реферат

CONTEXT AND OBJECTIVE: COVID-19 has become the most relevant medical issue globally. Despite several studies that have investigated clinical characteristics of COVID-19 patients, no data have been reported on the prevalence of vertebral fractures (VFs). Since VFs may influence cardiorespiratory function and disease outcomes, the aim of this study was to assess VFs prevalence and clinical impact in COVID-19. DESIGN AND PATIENTS: This was a retrospective cohort study performed at San Raffaele Hospital, a tertiary health care hospital in Italy. We included COVID-19 patients for whom lateral chest x-rays at emergency department were available. VFs were detected using a semiquantitative evaluation of vertebral shape on chest x-rays. RESULTS: A total of 114 patients were included in this study and thoracic VFs were detected in 41 patients (36%). Patients with VFs were older and more frequently affected by hypertension and coronary artery disease (P < 0.001, P = 0.007, P = 0.034; respectively). Thirty-six (88%) patients in VFs+ group compared to 54 (74%) in VFs- group were hospitalized (P = 0.08). Patients with VFs more frequently required noninvasive mechanical ventilation compared with those without VFs (P = 0.02). Mortality was 22% in VFs+ group and 10% in VFs- group (P = 0.07). In particular, mortality was higher in patients with severe VFs compared with those with moderate and mild VFs (P = 0.04). CONCLUSIONS: VFs may integrate the cardiorespiratory risk of COVID-19 patients, being a useful and easy to measure clinical marker of fragility and poor prognosis. We suggest that morphometric thoracic vertebral evaluation should be performed in all suspected COVID-19 patients undergoing chest x-rays.


Тема - темы
COVID-19/diagnosis , COVID-19/epidemiology , Spinal Fractures/epidemiology , Thoracic Vertebrae , Aged , COVID-19/complications , Cohort Studies , Comorbidity , Female , Humans , Italy/epidemiology , Male , Middle Aged , Prevalence , Prognosis , Radiography, Thoracic/statistics & numerical data , Retrospective Studies , SARS-CoV-2/physiology , Severity of Illness Index , Spinal Fractures/complications , Spinal Fractures/diagnosis , Spinal Fractures/diagnostic imaging , Thoracic Vertebrae/diagnostic imaging , Thoracic Vertebrae/injuries , Thoracic Vertebrae/pathology
3.
Eur Spine J ; 30(2): 468-474, 2021 02.
Статья в английский | MEDLINE | ID: covidwho-888202

Реферат

PURPOSE: We present an organized hospital plan for the management of Coronavirus disease (COVID-19) patients requiring emergency surgical interventions. To introduce a multidisciplinary approach for the management of COVID-19-infected patients and to report the first operated patient in the Corona unit. METHODS: A detailed presentation of the hospital plan for a separate Corona unit with its intensive care unit and operating rooms. Description of the management of the first spine surgery case treated in this unit. RESULTS: The Corona unit showed a practical approach for the management of an emergency cervical spine fracture-dislocation with acute paralysis. The patient is 92-year-old female. The mechanism of injury was a simple fall during the stay in the internal medicine department where the patient was treated in the referring hospital. The patient had no other injuries and was awake and oriented. The patient did not have the clinical symptom of COVID-19, and the test result of COVID-19 done in the referring hospital was not available on admission in our emergency room. Education of the medical staff and organization of the operating theatre facilitated the management of the patient without an increased risk of spreading the infection. CONCLUSIONS: The current COVID-19 pandemic requires an extra-ordinary organization of the medical and surgical care of the patients. It is possible to manage an infected or a potentially infected patient surgically, but a multidisciplinary plan is necessary to protect other patients and the medical staff.


Тема - темы
COVID-19/prevention & control , Cervical Vertebrae/injuries , Fracture Fixation, Internal/methods , Intensive Care Units/organization & administration , Joint Dislocations/surgery , Operating Rooms/organization & administration , Spinal Fractures/surgery , Zygapophyseal Joint/injuries , Accidental Falls , Aged, 80 and over , Cervical Vertebrae/diagnostic imaging , Cervical Vertebrae/surgery , Coronavirus , Coronavirus Infections , Emergency Service, Hospital , Environment Design , Female , Fractures, Bone , Germany , Hospital Design and Construction , Humans , Joint Dislocations/diagnostic imaging , Magnetic Resonance Imaging , Pandemics , Paraplegia/etiology , Personal Protective Equipment , SARS-CoV-2 , Spinal Fractures/complications , Spinal Fractures/diagnostic imaging , Zygapophyseal Joint/diagnostic imaging , Zygapophyseal Joint/surgery
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